Research Scientist

Tel: +65 6319 4783

Email: fchen@imre.a-star.edu.sg

Research Scientist, NanoBio Lab, Singapore, 2021-present

Postdoctoral Fellow, NanoBio Lab, Singapore, 2019-2021

Postdoctoral Fellow, Institute of Bioengineering and Nanotechnology, Singapore, 2016-2019

Research Fellow, National University of Singapore, 2014-2016

Research Assistant, National University of Singapore, 2013-2014

Ph.D. in Chemistry, National University of Singapore, 2013

M.Sc. in Medicinal Chemistry, Peking Union Medical College, Tsinghua University, China, 2008

B.Sc. in Pharmaceutical Sciences, Shandong University, China, 2005


  1. H. Liu, F. Chen, N. Zhao, S. V. C. Vummaleti, M. B. Sullivan, J. Y. Ying, and L. Wang, "Rhodium-Catalyzed Ring Expansion Reactions for the Concise Construction of Densely Functionalized Oxathionines and Oxathiocines," ACS Catal. 2022, 12, 13, 7524–7530

  2. A. Roy, H. Joshi, R. Ye, J. Shen, F. Chen, A. Aksimentiev and H. Zeng, “Polyhydrazide‐Based Organic Nanotubes as Efficient and Selective Artificial Iodide Channels,” Angewandte Chemie International Edition, 132 (2020) 4836-4843.

  3. J. Shen, R. Ye, A. Romanies, A. Roy, F. Chen, C. Ren, Z. Liu and H. Zeng, “An Aquafoldmer-Based Aquaporin-Like Synthetic Water Channel,” Journal of the American Chemical Society, 142 (2020) 10050-10058.

  4. H. Zeng, A. Roy, H. Joshi, R. Ye, J. Shen, F. Chen and A. Aksimentiev, “Polyhydrazide-Based Organic Nanotubes as Extremely Efficient and Highly Selective Artificial Iodide Channels,” Angew. Chem. Int. Ed., 59[12] (2020) 4806-4813

  5. H. Zeng, F. Chen, J. Shen, N. Li, A. Roy, R. Ye, and C. Ren, “Pyridine/Oxadiazole-Based Helical Foldamer Ion Channels with Exceptionally High K+/Na+ Selectivity,” Angew. Chem. Int. Ed., 59[4] (2019) 1440-1444

  6. R. Ye, C. Ren, J. Shen, F. Chen, N. Li, A. Roy, and H. Zeng, “Molecular Ion Fishers as Highly Active and Exceptionally Selective K+ Transporters,” J. Am. Chem. Soc., 141[25] (2019) 9788-9792

  7. L. Yuan, J. Shen, R. Ye, F. Chen and H. Q. Zeng, “Structurally Simple Trimesic Amides as Highly Selective Anion Channels,” Chem. Commun., 55 (2019) 4797-4800

  8. C. L. Ren, F. Chen, R. J. Ye, Y. S. Ong, H. F. Lu, S. S. Lee, J. Y. Ying and H. Q. Zeng, “Molecular Swings as Extremely Active Ion Transporters,” Angewandte Chemie International Edition, 58[24] (2019) 8034-8038

  9. C. Ren, F. Zeng, J. Shen, F. Chen, A. Roy, S. Zhou, H. Ren and H. Zeng, “Pore-Forming Monopeptides as Exceptionally Active Anion Channels,” Journal of the American Chemical Society, 140 (2018) 8817-8826

  10. C. Ren, X. Ding, A. Roy, J. Shen, S. Zhou, F. Chen, S. F. Yau Li, H. Ren, Y. Y. Yang and H. Zeng, “A Halogen Bond-Mediated Highly Active Artificial Chloride Channel with High Anticancer Activity,” Chemical Science, 9 (2018) 4044-4051

  11. C. Ren, J. Shen, F. Chen, and H. Zeng, “Rapid Room-Temperature Gelation of Crude Oils by a Wetted Powder Gelator,” Angew. Chem. Int. Ed., 56[14] (2017) 3847-3851

  12. W. Z. Yu, F. Chen, Y. A. Cheng, and Y. Y. Yeung, “Catalyst-Free and Metal-Free Electrophilic Bromoamidation of Unactivated Olefins Using the N-Bromosuccinimide/Sulfonamide Protocol,” The Journal of Organic Chemistry, 80[5] (2015) 2815-2821

  13. Z. Ke, C. K. Tan, F. Chen, and Y. Y. Yeung, “Catalytic Asymmetric Bromoetherification and Desymmetrization of Olefinic 1,3-Diols with C2-Symmetric Sulfides,” Journal of the American Chemical Society, 136[15] (2014) 5627-5630

  14. F. Chen, C. K. Tan, and Y. Y. Yeung, “C2 Symmetric Cyclic Selenium-Catalyzed Enantioselective Bromoaminocyclization,” Journal of the American Chemical Society, 135[4] (2013) 1232-1235

  15. C. K. Tan, F. Chen, and Y. Y. Yeung, “Studies Toward Lewis Basic Thiocarbamate and Thiourea Mediated Bromolactonization: The Effect of a Trace Amount of Water on the Reactivity and Enantioselectivity,” Tetrahedron Letters, 52[38] (2011) 4892-4895

  16. L. Zhou, C. K. Tan, X. Jiang, F. Chen, and Y. Y. Yeung, “Asymmetric Bromolactonization Using Amino-thiocarbamate Catalyst,” Journal of the American Chemical Society, 132[44] (2010) 15474-15476

  17. F. Chen, X. Jiang, J. C. Er, and Y. Y. Yeung, “Molecular Sieves as an Efficient and Recyclable Catalyst for Bromolactonization and Bromoacetoxylation Reactions,” Tetrahedron Letters, 51[26] (2010) 3433-3435


  1. H. Q. Zeng, A. Roy, F. Chen, J. Shen, “Polyhydrazides-Based Superpermeable Synthetic Water Channels”, Singapore Patent Granted in February of 2019