Research Projects

Nanocomposites

We are developing nanocomposites with controlled porosity and/or architecture for energy storage systems. We have developed novel materials for lithium-ion, lithium-sulfur and solid-state batteries, fuel cell and supercapacitor applications. These unique materials display superior capacity, charging efficiency, stability and safety than conventional materials.

Biomaterials

We have developed novel drug carriers derived from DNA nanogels and green tea-based micellar complexes as effective, safe delivery systems for drug and RNA therapies targeting cancer and various diseases. We have also generated novel nanoparticles as synthetic cell culture substrates and antimicrobial/antifouling systems. Our work also involves hydrogels for organoid culture for in vitro toxicology and drug screening.

Devices

We have incorporated nanosystems in device fabrication to facilitate the rapid and accurate detection of diseases, food pathogens, contaminants, and environmental pollutants.

Genotyping Assays

We have developed a microsieve to isolate circulating tumor cells from blood based on differences in cell size. This liquid biopsy offers non-invasive cancer diagnostics and monitoring to guide clinical treatment. The technology platform is paired with nanoprobes for companion diagnostics in the detection of genes associated with breast, cervical, colorectal, stomach, pancreatic, bladder and prostate cancers, and leukemia.

Agritechnology

In our hydroponics lab, we are developing microorganisms as natural, eco-friendly fertilizers that promote plant growth. The bacteria-based biofertilizers are encapsulated in nanostructured coatings on plant seeds to significantly improve germination. We have also synthesized green microparticles for the controlled release of nutrients in soil and cocopeat plugs.

Biosystems

We have developed novel safety screening models, microphysiological systems and organoid based technologies to predict organ toxicities in humans, monitor environmental toxicants, and develop personalized therapies.