shujun gao

G. Yi, S. Gao, H. Lu, W. Z. Khoo, S. Liu, S. Chng, Y. Y. Yang, J. Y. Ying, and Y. Zhang, “Surface Antimicrobial Treatment by Biocompatible, Vertically Aligned Layered Double Hydroxide Array,” Advanced Materials Interfaces 9 (9), 2101872

Y. Hu, S. Gao, H. Lu, and J. Y. Ying, “Acid-Resistant and Physiological pH-Responsive DNA Hydrogel Composed of A-Motif and i-Motif toward Oral Insulin Delivery,” Journal of the American Chemical Society 2022, 144, 12, 5461–5470

S. N. Riduan, G. Yi, S. Gao, J. P. K. Tan, Y. L. Tan, Y. Yuan, H. Lu, S. Chng, J. T. Ong, P. Y. Hon, M. Y. Abdad, S. Vasoo, B. S. P. Ang, Y. Y. Yang, J. Y. Ying, and Y. Zhang, “Evaluation of the ZnO Nanopillar Surface for Disinfection Applications,” ACS Applied Bio Materials 4 (10), 7524-7531

A. L. Z. Lee, C. Yang, S. Gao, Y. Wang, K. L. Hendrick, Y. Y. Yang, “Biodegradable Cationic Polycarbonates as Vaccine Adjuvants,” ACS Applied Materials and Interfaces, (2020) DOI: 10.1021/acsami.0c09649. IF: 8.330

W. Chin, G. Zhong, Q. Pu, C. Yang, W. Lou, P. F. De Sessions, B. Periaswamy, A. Lee, Z. C. Liang, X. Ding, S. Gao, C. W. Chu, S. Bianco, C. Bao, Y. W. Tong, W. Fan, M. Wu, J. L. Hedrick, Y. Y. Yang, “A Macromolecular Approach to Eradicate Multidrug Resistant Bacterial Infections While Mitigating Drug Resistance Onset,” Nature Communications, 9 (2018) 917

K. Liang, J. E. Chung, S. J. Gao, N. Yongvongsoontorn, M. Kurisawa, “Highly Augmented Drug Loading and Stability of Micellar Nanocomplexes Composed of Doxorubicin and Poly(ethylene glycol)-Green Tea Catechin Conjugate for Cancer Therapy,” Advanced Materials, (2018) DOI: 10.1002/adma.201706963

B. C. U. Tai, C. Du, S. Gao, A. C. A. Wan, “Synthetic Poly(vinylalcohol)-Based Membranes for Cartilage Surgery and Repair,” Biotechnology Journal: AFOB Special Issue on Stem Cells in Tissue Engineering and Regenerative Medicine, 12 (2017) 1700134

J. P. K. Tan, D. J. Coady, H. Sardon, A. Yuen, S. Gao, S. W. Lim, Z. C. Liang, E. W. Tan, S. Venkataraman, A. C. Engler, M. Fevre, R. On, Y. Y. Yang, J. L. Hedrick, “Broad Spectrum Macromolecular Antimicrobials with Biofilm Disruption Capability and In Vivo Efficacy,” Advanced Healthcare Materials, 6 (2017) 1601420

S. Liu, R. J. Ono, H. Wu, J. Y. Teo, Z. C. Liang, K. Xu, M. Zhang, G. Zhong, J. P. K. Tan, M. Ng, C. Yang, J. Chan, Z. Ji, C. Bao, K. Kumar, S. Gao, A. Lee, M. Fevre, H. Dong, J. Y. Ying, L. Li, W. Fan, J. L. Hedrick, Y. Y. Yang, “Highly Potent Antimicrobial Polyionenes with Rapid Killing Kinetics, Skin Biocompatibility and In Vivo Bactericidal Activity,” Biomaterials, 127 (2017) 36-48

J. M. W. Chan, R. J. Wojtecki, H. Sardon, A. L. Z. Lee, C. E. Smith, A. Shkumatov, S. Gao, H. Kong, Y. Y. Yang, J. L. Hedrick, “Self-Assembled, Biodegradable Magnetic Resonance Imaging Agents: Organic Radical-Functionalized Diblock Copolymers,” ACS Macro Letters, 6 (2017) 176-180

K. H. Bae, S. Tan, A. Yamashita, W. X. Ang, S. J. Gao, S. Wang, J. E. Chung, M. Kurisawa, “Hyaluronic Acid-Green Tea Catechin Micellar Nanocomplexes: Fail-Safe Cisplatin Nanomedicine for the Treatment of Ovarian Cancer Without Off-Target Toxicity,” Biomaterials, 148 (2017) 41-53

K. Ichiyama, C. Yang, L. Chandrasekaran, S. Liu, L. Rong, Y. Zhao, S. Gao, A. Lee, K. Ohba, Y. Suzuki, Y. Yoshinaka, K. Shimotohno, K. Miyakawa, A. Ryo, J. Hedrick, N. Yamamoto, Y. Y. Yang, “Cooperative Orthogonal Macromolecular Assemblies with Broad Spectrum Antiviral Activity, High Selectivity, and Resistance Mitigation,” Macromolecules, 49[7] (2016) 2618-2629

J. M. W. Chan, J. P. K. Tan, A. C. Engler, X. Ke, S. Gao, C. Yang, H. Sardon, Y. Y. Yang, J. L. Hedrick, “Organocatalytic Anticancer Drug Loading of Degradable Polymeric Mixed Micelles via a Biomimetic Mechanism,” Macromolecules, 49[6] (2016) 2013-2021

K. Liang, K. H. Bae, F. Lee, K. Xu, J. E. Chung, S. J. Gao, M. Kurisawa, “Self-Assembled Ternary Complexes Stabilized with Hyaluronic Acid-Green Tea Catechin Conjugates for Targeted Gene Delivery,” Journal of Controlled Release, 226 (2016) 205-216

K. Xu, F. Lee, S. Gao, M.-H. Tan, M. Kurisawa, “Hyaluronidase-Incorporated Hyaluronic Acid–Tyramine Hydrogels for the Sustained Release of Trastuzumab,” Journal of Controlled Release, 216 (2015) 47-55

K. Xu, K. Narayanan, F. Lee, K. H. Bae, S. Gao, M. Kurisawa, “Enzyme-Mediated Hyaluronic Acid–Tyramine Hydrogels for the Propagation of Human Embryonic Stem Cells in 3D,” Acta Biomaterialia, 24 (2015) 159-171

C. D. Ren, S. Gao, M. Kurisawa, J. Y. Ying, “Cartilage Synthesis in Hyaluronic Acid-Tyramine Constructs,” Journal of Materials Chemistry B, 3[9] (2015) 1942-1956

C. Yang, S. Q. Liu, S. Venkataraman, S. J. Gao, X. Y. Ke, X. T. Chia, J. L. Hedrick, Y. Y. Yang, “Structure-Directing Star-Shaped Block Copolymers: Supramolecular Vesicles for the Delivery of Anticancer Drugs,” Journal of Controlled Release, 208 (2015) 93-105

A. C. Engler, X. Ke, S. Gao, J. M. W. Chan, D. J. Coady, R. J. Ono, R. Lubbers, A. Nelson, Y. Y. Yang, J. L. Hedrick, “Hydrophilic Polycarbonates: Promising Degradable Alternatives to Poly(ethylene glycol)-Based Stealth Materials,” Macromolecules, 48[6] (2015) 1673-1678

A. L. Z. Lee, V. W. L. Ng, S. Gao, J. L. Hedrick, Y. Y. Yang, “Injectable Biodegradable Hydrogels from Vitamin D.Functionalized Polycarbonates for the Delivery of Avastin with Enhanced Therapeutic Efficiency against Metastatic Colorectal Cancer,” Biomacromolecules, 16[2] (2015) 465-475

J. E. Chung, S. Tan, S. J. Gao, N. Yongvongsoontorn, S. H. Kim, J. H. Lee, H. S. Choi, H. Yano, L. Zhuo, S. Krishnamurthy, V. W. L. Ng, S. Gao, M.-H. Tan, Y. Y. Yang, “Phenformin-Loaded Polymeric Micelles for Targeting Both Cancer Cells and Cancer Stem Cells In Vitro and In Vivo,” Biomaterials, 35[33](2014) 9177-9186

H. F. Lu, C. Chai, T. C. Lim, M. F. Leong, J. K. Lim, S. Gao, K. L. Lim, A. C. A. Wan, “A Defined Xeno-Free and Feeder-Free Culture System for the Derivation, Expansion and Direct Differentiation of Transgene-Free Patient-Specific Induced Pluripotent Stem Cells,” Biomaterials, 35[9] (2014) 2816-2826

L.-S. Wang, C. Du, W. S. Toh, A. C. A. Wan, S. J. Gao, M. Kurisawa, “Modulation of Chondrocyte Functions and Stiffness-Dependent Cartilage Repair Using An Injectable Enzymatically Crosslinked Hydrogel with Tunable Mechanical Properties,” Biomaterials, 35 (2014) 2207-2217

X.-Y. Ke, V. W. L. Ng, S.-J. Gao, Y. W. Tong, J. L. Hedrick, Y. Y. Yang, “Co-Delivery of Thioridazine and Doxorubicin Using Polymeric Micelles for Targeting Both Cancer Cells and Cancer Stem Cells,” Biomaterials, 35[3] (2014) 1096-1108

Y. Wang, N. L. Ibrahim, J. Jiang, S. Gao, N. Erathodiyil, J. Y. Ying, “Construction of Block Copolymers for the Coordinated Delivery of Doxorubicin and Magnetite Nanocubes,” Journal of Controlled Release, 169[3] (2013) 211-219

A. L. Z. Lee, V. W. L. Ng, S. Gao, J. L. Hedrick, Y. Y. Yang, “Injectable Hydrogels from Triblock Copolymers of Vitamin E-Functionalized Polycarbonate and Poly(Ethylene Glycol) for Subcutaneous Delivery of Antibodies for Cancer Therapy,” Advanced Functional Materials, 24[11] (2013) 1538-1550

Z. Y. Ong, C. Yang, S. J. Gao, X. Y. Ke, J. L. Hedrick, Y. Y. Yang, “Galactose-Functionalized Cationic Polycarbonate Diblock Copolymer for Targeted Gene Delivery to Hepatocytes,” Macromolecular Rapid Communications, 34 (2013) 1714-1720

K. Narayanan, V. Y. Lim, J. Shen, Z. W. Tan, D. Rajendran, S.-C. Luo, S. Gao, A. C. A. Wan, J. Y. Ying, “Extracellular Matrix-Mediated Differentiation of Human Embryonic Stem Cells: Differentiation to Insulin-Secreting Beta Cells,” Tissue Engineering Part A, 20[1-2] (2013) 424-433

T. C. Lim, M. F. Leong, H. Lu, C. Du, S. Gao, A. C. A. Wan, J. Y. Ying, “Follicular Dermal Papilla Structures by Organization of Epithelial and Mesenchymal Cells in Interfacial Polyelectrolyte Complex Fibers,” Biomaterials, 34[29] (2013) 7064-7072

Z. Y. Ong, S. J. Gao, Y. Y. Yang, “Short Synthetic ß-Sheet Forming Peptide Amphiphiles as Broad Spectrum Antimicrobials with Antibiofilm and Endotoxin Neutralizing Capabilities,” Advanced Functional Materials, 23[29] (2013) 3682-3692

A. B. Ebrahim Attia, C. Yang, J. P. K. Tan, S. Gao, D. F. Williams, J. L. Hedrick, Y.-Y. Yang, “The Effect of Kinetic Stability on Biodistribution and Anti-Tumor Efficacy of Drug-Loaded Biodegradable Polymeric Micelles,” Biomaterials, 34 (2013) 3132-3140

K. Xu, F. Lee, S. J. Gao, J. E. Chung, H. Yano, M. Kurisawa, “Injectable Hyaluronic Acid-Tyramine Hydrogels Incorporating Interferon-a2a for Liver Cancer Therapy,” Journal of Controlled Release, 166 (2013) 203-210

K. Narayanan, K. M. Schumacher, F. Tasnim, K. Kandasamy, A. Schumacher, M. Ni, S. Gao, B. Gopalan, H. F. Lu, S.-X. Lim, M. F. Leong, K. Narayanan, R. P. K. Toh, S. Gao, A. C.A. Wan, “Efficient Neuronal Differentiation and Maturation of Human Pluripotent Stem Cells Encapsulated in 3D Microfibrous Scaffolds,” Biomaterials, 33[36] (2012) 9179-9187

L. Liu, Y. Huang, S. N. Riduan, S. Gao, Y. Yang, W. Fan, Y. Zhang, “Main-Chain Imidazolium Oligomer Material as a Selective Biomimetic Antimicrobial Agent,” Biomaterials, 33[33] (2012) 8625-8631

M. Khan, C. Y. Ang, N. Wiradharma, L.-K. Yong, S. Liu, L. Liu, S. Gao, Y.-Y. Yang, “Diaminododecane-based Cationic Bolaamphiphile as a Non-Viral Gene Delivery Carrier,” Biomaterials, 33[18] (2012) 4673-4680

Y. Y. Lee, K. Narayanan, S. J. Gao, J. Y. Ying, “Elucidating Drug Resistance Properties in Scarce Cancer Stem Cells using Droplet Microarray,” Nano Today, 7 (2012) 29-34

C. Yang, A. B. Ebrahim Attia, J. P. K. Tan, X. Ke, S. Gao, J. L. Hedrick, Y.-Y. Yang, “The Role of Non-Covalent Interactions in Anticancer Drug Loading and Kinetic Stability of Polymeric Micelles,” Biomaterials, 33[10] (2012) 2971-2979

H. F. Lu, K. Narayanan, S. X. Lim, S. Gao, M. F. Leong, A. C. A. Wan, “3D Microfibrous Scaffold for Long-Term Human Pluripotent Stem Cell Self-Renewal and Storage under Chemically Defined Conditions,” Biomaterials, 33[8] (2012) 2419-2430

A. L. Z. Lee, S. Venkataraman, S. B. M. Sirat, S. Gao, J. L. Hedrick, Y. Y. Yang, “The Use of Cholesterol-Containing Biodegradable Block Copolymers to Exploit Hydrophobic Interactions for the Delivery of Anticancer Drugs,” Biomaterials, 33[6] (2011) 1921-1928

S. L. J. Ng, K. Narayanan, S. Gao, A. C. A. Wan, “Lineage Restricted Progenitors for the Repopulation of Decellularized Heart,” Biomaterials, 32[30] (2011) 7571-7580

Y. Zhang, M. Tan, H. Li, Y. Zheng, S. Gao, H. Zhang, J. Y. Ying, “Mesoscopic Organic Nanosheets Peeled from Stacked 2D Covalent Frameworks,” Chemical Communications, 47 (2011) 7365-7367

F. Nederberg, Y. Zhang, J. P. K. Tan, K. Xu, H. Wang, C. Yang, S. Gao, X. D. Guo, K. Fukushima, L. Li, J. Hedrick*, Y.-Y. Yang*, “Biodegradable Nanostructures with Selective Lysis of Microbial Membranes,” Nature Chemistry, 3 (2011) 409-414 *These authors contributed equally.

Z. Yue, F. Wen, S. Gao, M. Y. Ang, P. K. Pallathadka, L. Liu, H. Yu, “Preparation of Three-Dimensional Interconnected Macroporous Cellulosic Hydrogels for Soft Tissue Engineering,” Biomaterials, 31[32](2010) 8141-8152

B. C. U. Tai, D. Chan, S. J. Gao, A. C. A. Wan, J. Y. Ying, “The Use of a Polyelectrolyte Fibrous Scaffold to Deliver Differentiated hMSCs to the Liver,” Biomaterials, 31[1] (2010) 48-57

K. Narayanan, K. J. Leck, S. Gao, A. C. A. Wan, “Three-Dimensional Reconstituted Extracellular Matrix Scaffolds for Tissue Engineering,” Biomaterials, 30 (2009) 4309-4317

Y. S. Pek, M. Kurisawa, S. Gao, J. E. Chung, J. Y. Ying, “The Development of a Nanocrystalline Apatite Reinforced Crosslinked Hyaluronic Acid-Tyramine Composite as an Injectable Bone Cement,” Biomaterials 30 (2009) 822-828

Y. S. Pek, S. Gao, M. S. Mohamed Arshad, K.-J. Leck, J. Y. Ying, “Porous Collagen-Apatite Nanocomposite Foams as Bone Regeneration Scaffolds,” Biomaterials 29 (2008) 4300-4305

Y. Zheng, S. Gao, J.Y. Ying, “Glutathione-Capped CdTe QDs: Synthesis and Applications in Cell Imaging,” Advanced Materials, 19 (2007) 376-380

T. B. Bini, S. Gao, S. Wang, S. Ramakrishna, “Poly(l-lactide-co-glycolide) Biodegradable Microfibers and Electrospun Nanofibers for Nerve Tissue Engineering : An In Vitro Study,” Journal of Materials Science, 41[19] (2006) 6453-6459

Y. Wang, S. J. Gao, H. Wen, H. S. Yoon, Y. Y. Yang, “Novel Cationic Core-shell Nanoparticles Self-assembled from a Biodegradable Amphiphilic Copolymer for the Co-delivery of Drugs and DNA,” Nature Materials, 5[10] (2006) 791-796

L. Liu, S. Gao, Y. Yu, R. Wang, D. T. Liang, S. Liu, “Bio-Ceramic Hollow Fiber Membranes for Immunoisolation and Gene Delivery: I: Membrane Development,” Journal of Membrane Science, 280 (2006) 375-382

T. B. Bini, S. Gao, S. Wang, S. Ramakrishna, “Development of Fibrous Biodegradable Polymer Conduits for Guided Nerve Regeneration,” Journal of Materials Science: Materials in Medicine, 16[4] (2005) 367-375

M. Kurisawa, J. E. Chung, Y. Y. Yang, S. J. Gao, H. Uyama, “Injectable Biodegradable hydrogels Composed of Hyaluronic Acid-tyramine Conjugates for Drug Delivery and Tissue Engineering,” Chemical Communications, 34 (2005) 4312-4314

T. B. Bini, S. Gao, T. T. Chan, S. Wang, A. Lim, L. B. Hai, S. Ramakrishna, “Electrospun Poly(l-lactide-co-glycolide) Biodegradable Polymer Nanofiber Tubes for Peripheral Nerve Regeneration,” Nanotechnology, 15 (2004) 1459-1464

T. B. Bini, S. Gao, X. Xu, S. Wang, S. Ramakrishna, K. W.Leong, “Peripheral Nerve Regeneration by Microbraided poly(L-lactide-co-glycolide) Biodegradable Polymer Fibers,” Journal of Biomedical Materials Research, 68A (2004) 286-295

J. Wang, S.-J. Gao, P.-C. Zhang, S. Wang, H.-Q. Mao, K. W. Leong, “Polyphosphoramidate Gene Carriers: Effect of Charge Group on Gene Transfer Efficiency,” Gene Therapy, 11[12] (2004) 1001-1010

Y. Li, J. Wang, C. Lee, C. Y. Wang, S. J. Gao, G. P. Tong, Y. X. Ma, B. Soon, C. T. Lim, H. Yu, H.-Q. Mao, K. W. Leong, S. Wang, “CNS Gene Transfer Facilitated by a Novel Controlled Release System Based on DNA Complexes of Degradable Polycation PPE-EA: A Comparison with Polyethylenimine/DNA Complexes,” Gene Therapy, 11 (2004) 109-114

S. C. H. Wong, L. L. Ong, C. P. N. Er, S. Gao, H. Yu, J.B.Y. So, “Cloning of Rat Telomerase Catalytic Subunit Functional Domains,” Reconstitution of Telomerase Activity and Enzymatic Profile of Pig and Chicken Tissues Life Science, 73 (2003) 2749-2760

G. P. Tang, J. M. Zeng, S. J. Gao, Y. X. Ma, L. Shi, S. Wang, “Polyethylene Glyco Modified Polyethylenimine for Improved CNS Gene Transfer: Effect of PEGylation Extent,” Biomaterials, 24 (2003) 2351-2362

L. Shi, G. P. Tang, S. J. Gao, Y. X. Ma, B. H. Liu, Y. Li, S. Wang, “Repeated Intrathecal Administration of Plasmid DNA Complexed with Polyethylene Glycol-Grafted Polyethylenimine Led to Prolonged Transgene Expression in the Spinal Cord,” Gene Therapy, 10 (2003) 1179-1188

X. Y. Xu, W.-C. Yee, P. Y. K. Hwang, H. Yu, A. C. A. Wan, S. J. Gao, K.-L. Boon, H.-Q. Mao, K. W. Leong, S. Wang, “Peripheral Nerve Regeneration with Sustained Released of Polyphosphoester Microencapsulated NGF Within Nerve Guide Conduits,” Biomaterials, 24[13] (2003) 2405-2412

X. Y. Xu, H. Yu, S. J. Gao, H.-Q. Mao, K. W. Leong, S. Wang, “Polyphosphester Microspheres for Sustained Release of Biologically Active Nerve Growth Factor,” Biomaterials, 23 (2002) 3765-3772

S. Wang, N. Ma, S. J. Gao, H. Yu, K. W. Leong, “Gene Expression in the Brainstem Effected by Intramuscular Injections of Polymeric DNA Complexes,” Molecular Therapy, 3 (2001) 658-664

S. Wang, A. C. A. Wan, X. Y. Xu, S. J. Gao, H.-Q. Mao, K. W. Leong, H. Yu, “A New Nerve Guide Conduit Material Composed of a Biodegradable Poly(phosphoester),” Biomaterials, 22 (2001) 1157-1169

S.-M. Chia, L. Jun, X. Xi, K.W. Leong, S. Gao, H. Yu, “Hepatocyte Encapsulation for Enhanced Cellular Functions,” Tissue Engineering, 6[5] (2000) 481-495

J. Y. Ying, Y. S. Pek, S. Gao, M. S. Mohamed Arshad, P. L. Mao, “Porous Collagen-Inorganic Tissue Scaffolds for Orthopaedic and Other Load-Bearing Application,” European Patent Granted on November 7, 2012

E. Chow, J. Y. Ying, S. Gao, “Nanoemulsions for Transdermal Delivery: A New Vehicle for Dermocosmetics,” Singapore Patent Granted on September 28, 2012

J. Y. Ying, Y. S. Pek, S. Gao, M. S. M. Arshad, P. Mao, “Porous Collagen-Inorganic Tissue Scaffolds for Orthopaedic and Other Load-Bearing Application,” Singapore Patent Granted on August 31, 2009

J. Y. Ying, Y. Zheng, S. Gao, “Synthesis and Bioimaging Applications of Glutathione-Capped CdTe Quantum Dots,” Singapore Patent Granted on September 30, 2008